EVproDX

A non-invasive test for early detection of patients with aggressive prostate cancer.

A simple blood test that can identify patients with aggressive prostate cancer, without the need for biopsy

About Us

We are a team of researchers and clinicians who are currently working on  improving diagnosis of aggressive prostate cancer.

Our research focuses on the role of extracellular vesicles (EVs) as drivers of aggressive prostate cancer. By detecting EVs in the blood we can gain valuable information about a patient’s cancer.

A non-invasive test can play a vital role in screening aggressive prostate cancer.

A non-invasive test can play a vital role in early detection of prostate cancer.

We have discovered that cancer-derived EVs can regulate the tumour microenvironment, making it more favourable for cancer growth and spread. We have developed a novel, non-invasive test that can detect cancer EVs in the blood and distinguish between aggressive and low-risk prostate cancers.

This test has the potential to improve the accuracy and reliability of prostate cancer detection and save men’s lives.

Human cells segregating exosomes. Exosomes are extracellular vesicles, that are involved in physiological processes like coagulation, waste management and intercellular communication. They are found in biological fluids including saliva, blood,  cerebrospinal fluid and urine.

The Problem

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New Prostate Cancer Cases

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Prostate Cancer Deaths

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New Cases (UK)

Prostate cancer is the second most common cancer and the fifth leading cause of cancer death among men worldwide, with an estimated 1,414,259 new cases and 375,304 deaths in 2020. In the UK, there are around 52,300 new cases of prostate cancer every year and around 12,000 deaths from prostate cancer.

Current diagnostic tests like PSA (Prostate-Specific Antigen) lack sufficient accuracy for early identification of patients at risk of aggressive disease, and accurate diagnosis often requires biopsy.

The only way to confirm prostate cancer is by taking a tissue sample from the prostate (a biopsy). This is an invasive and risky procedure that can cause infection, bleeding, pain, and other problems.

To confirm diagnosis of prostate cancer it is often necessary to take a tissue sample from the prostate (called a biopsy). This is an invasive and risky procedure that can cause infection, bleeding, pain and other problems.

Many men have biopsies that are not needed or show low-risk prostate cancer that does not need treatment. This wastes time, money, and resources and harms the quality of life of men with prostate cancer.

Therefore, there is a need for better non-invasive tests to enable early identification of patients with aggressive prostate cancer.

Middle age handsome man smiling happy holding blue prostate cancer ribbon at the city.

Why EVproDX?

EVproDX is a revolutionary screening test for prostate cancer that offers many advantages over the current methods. Unlike the PSA blood test, which is unreliable and can give false results, EVproDX can accurately detect cancer-derived extracellular vesicles (EVs) in the blood and distinguish between aggressive and low-risk prostate cancers.

Unlike the biopsy, which is invasive and risky, EVproDX is non-invasive and safe and does not require any special equipment or staff.

By limiting the need for invasive biopsy, we will improve the lives of patients with prostate cancer.

EVproDX is a rapid test that works with a blood sample that can provide results within a reasonable time, allowing patients who need treatment to be identified much sooner and have their treatment strategy tailored to their specific disease.

BloodTest

EVproDX can be repeated as often as needed, enabling patients to be monitored regularly and have any changes in their disease status reported promptly. This can improve the outcomes and well-being of patients with prostate cancer and reduce the costs and burden for the health care system.

EVproDX has promising results for aggressive prostate cancer screening. It is a non-invasive, accurate, and rapid test that can help men make informed decisions about their health and improve their quality of life.

BloodTest2

Our Solution

  • Non-invasive and accurate

    EVproDX can detect cancer-derived EVs in the blood or urine sample and distinguish between aggressive and low-risk prostate cancer without the need for a biopsy.

  • Rapid, simple and cost-effective

    EVproDX can provide results within a reasonable time without needing special equipment or staff. This can save time and resources for the patients and the health care system.

  • Tailored and informed

    EVproDX can help patients who need treatment to be identified much sooner and have their prostate cancer treatment strategy customized to their specific disease. This can improve the effectiveness and safety of the treatment and reduce the risk of overtreatment or undertreatment.

  • Repeatable and monitorable

    EVproDX can be repeated as often as needed, allowing patients to be monitored regularly and have any changes in their disease status reported promptly. This can improve the outcomes and well-being of patients with prostate cancer and help them adjust their treatment plan accordingly.

  • Adaptable and versatile

    EVproDX can be evolved as new biomarkers are identified. This can increase the scope and utility of the test and benefit more patients.

Meet Our Team

Dr Jason Webber

Dr Jason Webber

Chief Executive Officer / Co-Founder

Swansea University

Dr Ffion Walters

Dr Ffion Walters

Technology Transfer Officer

Swansea University

Prof Aled Clayton

Prof Aled Clayton

Chief Scientific Officer / Co-founder

Cardiff University

Mr Gokul Vignesh Kanda Swamy

Mr Gokul Vignesh Kanda Swamy

Clinical Lead

Swansea University

Dr Demi Pritchard

Dr Demi Pritchard

Research Lead

Swansea University

Register Your Interest

Click the button below to get in contact with us and learn more about our test.

Share Your Insights

Do you want to help influence the future of early detection screening and to help fight prostate cancer?

Click the button below to take our survey and help us to take the fight to prostate cancer.

 

Contact Us

To register your interest and learn more about our test, please use the contact form below to get in touch with our team. We are particularly keen to hear from healthcare providers, clinicians, manufacturers of diagnostic tests/assays, prostate cancer patients (and their representatives), executive non-departmental public bodies, manufacturers of research tools/consumables, and scientific researchers.